The largest study conducted so far with respect to the application of transcranial direct and alternating current stimulation in the treatment of depression was published by Brunoni. The author asserted that he made a controlled trial with over 120 patients suffering from depression. This resulted in a factorial study in which the patients subjected randomly to receive active tDCS and serum sertraline/placebo exhibited significant symptoms as compared to the patients that were given active tDCS and also in combination with sertraline.
As a result, further randomized clinical trials that aim to evaluate the clinical efficacy of tDCS in depression are being performed worldwide.
Here are some of the benefits of using transcranial direct and alternating current stimulation in the treatment of depression:
Transcranial alternating and direct current stimulation improves memory
The use of theta waves on the left parietal of a depressed patient helps to increase the working memory as well as factual memory as shown in 12 ADHD children. It is interesting to note that this only works when the theta waves are in the synchronization phase. Similar research conducted on 12 healthy female children reveals that it increases the memory confidence.
Transcranial direct and alternating current stimulation changes the brain waves thereby fighting depression
Three different studies were conducted on humans for about 20 minutes and it was discovered that transcranial direct and alternating current significantly increased the brain power for about 30 minutes in the indicated wavelength range.
Transcranial direct and alternating current stimulation is an appealing treatment for depression as a result of its relative safety and efficacy profiles attached to the fact of its relative inexpensiveness. TDCS have also been found to have tangible anti-depressant effects. It is also considered a promising therapy because of its minimally invasive nature and its benign relative adverse effects.
However, further research is required to examine the utility of transcranial direct and alternating current stimulation as the first treatment to think about in more severe forms of depression. Presently, it seems crucial to consider transcranial direct and alternating current stimulation as a treatment for patients with a mild level of depression without resistance to treatment. It may be just as effective to make use of it in enhancing the first kind of response rates when combined with pharmacotherapy and psychotherapy.
1Antal, A., Boros, K., Poreisz, C., Chaieb, L., Terney, D., & Paulus, W. (2008). Comparatively weak after-effects of transcranial alternating current stimulation (tACS) on cortical excitability in humans. Brain stimulation, 1(2), 97-105.